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Structural and molecular basis of ZNRF3/RNF43 transmembrane ubiquitin ligase inhibition by the Wnt agonist R-spondin., Zebisch M, Xu Y, Krastev C, MacDonald BT, Chen M, Gilbert RJ, He X, Jones EY., Nat Commun. January 1, 2013; 4 2787.              


Soft matter models of developing tissues and tumors., Gonzalez-Rodriguez D, Guevorkian K, Douezan S, Brochard-Wyart F., Science. November 16, 2012; 338 (6109): 910-7.


Stable intronic sequence RNA (sisRNA), a new class of noncoding RNA from the oocyte nucleus of Xenopus tropicalis., Gardner EJ, Nizami ZF, Talbot CC, Gall JG., Genes Dev. November 15, 2012; 26 (22): 2550-9.


Social discrimination by quantitative assessment of immunogenetic similarity., Villinger J, Waldman B., Proc Biol Sci. November 7, 2012; 279 (1746): 4368-74.


Study of the DNA damage checkpoint using Xenopus egg extracts., Willis J, DeStephanis D, Patel Y, Gowda V, Yan S., J Vis Exp. November 5, 2012; (69): e4449.


Stimulation of the Na(+)-coupled glucose transporter SGLT1 by B-RAF., Pakladok T, Hosseinzadeh Z, Alesutan I, Lang F., Biochem Biophys Res Commun. November 2, 2012; 427 (4): 689-93.


Structure-activity relationship of fenamates as Slo2.1 channel activators., Garg P, Sanguinetti MC., Mol Pharmacol. November 1, 2012; 82 (5): 795-802.


Significance of short chain fatty acid transport by members of the monocarboxylate transporter family (MCT)., Moschen I, Bröer A, Galić S, Lang F, Bröer S., Neurochem Res. November 1, 2012; 37 (11): 2562-8.


Spatial and temporal expressions of prune reveal a role in Müller gliogenesis during Xenopus retinal development., Bilitou A, De Marco N, Bello AM, Garzia L, Carotenuto P, Kim M, Campanella C, Ohnuma S, Zollo M., Gene. November 1, 2012; 509 (1): 93-103.                        


Subtype specificity interaction of bactridines with mammalian, insect and bacterial sodium channels under voltage clamp conditions., Peigneur S, Sevcik C, Tytgat J, Castillo C, D'Suze G., FEBS J. November 1, 2012; 279 (21): 4025-38.


Susceptibility of Xenopus laevis tadpoles to infection by the ranavirus Frog-Virus 3 correlates with a reduced and delayed innate immune response in comparison with adult frogs., De Jesús Andino F, Chen G, Li Z, Grayfer L, Robert J., Virology. October 25, 2012; 432 (2): 435-43.


Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline., Alijevic O, Kellenberger S., J Biol Chem. October 19, 2012; 287 (43): 36059-70.


Single-cell metabolomics: changes in the metabolome of freshly isolated and cultured neurons., Nemes P, Knolhoff AM, Rubakhin SS, Sweedler JV., ACS Chem Neurosci. October 17, 2012; 3 (10): 782-92.      


Signaling crosstalk between TGFβ and Dishevelled/Par1b., Mamidi A, Inui M, Manfrin A, Soligo S, Enzo E, Aragona M, Cordenonsi M, Wessely O, Dupont S, Piccolo S., Cell Death Differ. October 1, 2012; 19 (10): 1689-97.                    


Structural changes of regulatory domain heterodimer of N-methyl-D-aspartate receptor subunits GluN1 and GluN2B through the binding of spermine and ifenprodil., Tomitori H, Suganami A, Saiki R, Mizuno S, Yoshizawa Y, Masuko T, Tamura Y, Nishimura K, Toida T, Williams K, Kashiwagi K, Igarashi K., J Pharmacol Exp Ther. October 1, 2012; 343 (1): 82-90.


Simulated annealing reveals the kinetic activity of SGLT1, a member of the LeuT structural family., Longpré JP, Sasseville LJ, Lapointe JY., J Gen Physiol. October 1, 2012; 140 (4): 361-74.              


Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors., Venskutonytė R, Frydenvang K, Valadés EA, Szymańska E, Johansen TN, Kastrup JS, Pickering DS., ChemMedChem. October 1, 2012; 7 (10): 1793-8.


Signaling dynamics and embryonic development., Warmflash A, Siggia ED, Brivanlou AH., Cell Cycle. October 1, 2012; 11 (19): 3529-30.  


Studying mechanisms of regeneration in amphibian and reptilian vertebrate models., Kusumi K, Fisher RE., Anat Rec (Hoboken). October 1, 2012; 295 (10): 1529-31.  


Sizzled is unique among secreted frizzled-related proteins for its ability to specifically inhibit bone morphogenetic protein-1 (BMP-1)/tolloid-like proteinases., Bijakowski C, Vadon-Le Goff S, Delolme F, Bourhis JM, Lécorché P, Ruggiero F, Becker-Pauly C, Yiallouros I, Stöcker W, Dive V, Hulmes DJ, Moali C., J Biol Chem. September 28, 2012; 287 (40): 33581-93.


Self-regulation of the head-inducing properties of the Spemann organizer., Inui M, Montagner M, Ben-Zvi D, Martello G, Soligo S, Manfrin A, Aragona M, Enzo E, Zacchigna L, Zanconato F, Azzolin L, Dupont S, Cordenonsi M, Piccolo S., Proc Natl Acad Sci U S A. September 18, 2012; 109 (38): 15354-9.                            


Stoichiometry of the human glycine receptor revealed by direct subunit counting., Durisic N, Godin AG, Wever CM, Heyes CD, Lakadamyali M, Dent JA., J Neurosci. September 12, 2012; 32 (37): 12915-20.


Spontaneous formation of IpaB ion channels in host cell membranes reveals how Shigella induces pyroptosis in macrophages., Senerovic L, Tsunoda SP, Goosmann C, Brinkmann V, Zychlinsky A, Meissner F, Kolbe M., Cell Death Dis. September 6, 2012; 3 e384.            


Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine., Pan J, Chen Q, Willenbring D, Mowrey D, Kong XP, Cohen A, Divito CB, Xu Y, Tang P., Structure. September 5, 2012; 20 (9): 1463-9.


SUMOylated SoxE factors recruit Grg4 and function as transcriptional repressors in the neural crest., Lee PC, Taylor-Jaffe KM, Nordin KM, Prasad MS, Lander RM, LaBonne C., J Cell Biol. September 3, 2012; 198 (5): 799-813.              


Schistosoma mansoni: structural and biochemical characterization of two distinct Venus Kinase Receptors., Gouignard N, Vanderstraete M, Cailliau K, Lescuyer A, Browaeys E, Dissous C., Exp Parasitol. September 1, 2012; 132 (1): 32-9.


Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1., Illing AC, Shawki A, Cunningham CL, Mackenzie B., J Biol Chem. August 31, 2012; 287 (36): 30485-96.


Single mutation to a sex pheromone receptor provides adaptive specificity between closely related moth species., Leary GP, Allen JE, Bunger PL, Luginbill JB, Linn CE, Macallister IE, Kavanaugh MP, Wanner KW., Proc Natl Acad Sci U S A. August 28, 2012; 109 (35): 14081-6.


Structural insights into neuronal K+ channel-calmodulin complexes., Mruk K, Shandilya SM, Blaustein RO, Schiffer CA, Kobertz WR., Proc Natl Acad Sci U S A. August 21, 2012; 109 (34): 13579-83.


Sizzled-tolloid interactions maintain foregut progenitors by regulating fibronectin-dependent BMP signaling., Kenny AP, Rankin SA, Allbee AW, Prewitt AR, Zhang Z, Tabangin ME, Shifley ET, Louza MP, Zorn AM., Dev Cell. August 14, 2012; 23 (2): 292-304.                                


Subfunctionalization and neofunctionalization of vertebrate Lef/Tcf transcription factors., Klingel S, Morath I, Strietz J, Menzel K, Holstein TW, Gradl D., Dev Biol. August 1, 2012; 368 (1): 44-53.              


Suppression of Bmp4 signaling by the zinc-finger repressors Osr1 and Osr2 is required for Wnt/β-catenin-mediated lung specification in Xenopus., Rankin SA, Gallas AL, Neto A, Gómez-Skarmeta JL, Zorn AM., Development. August 1, 2012; 139 (16): 3010-20.                                                                                


Seeing the Warburg effect in the developing retina., Fiske BP, Vander Heiden MG., Nat Cell Biol. August 1, 2012; 14 (8): 790-1.


Selective regulation of maize plasma membrane aquaporin trafficking and activity by the SNARE SYP121., Besserer A, Burnotte E, Bienert GP, Chevalier AS, Errachid A, Grefen C, Blatt MR, Chaumont F., Plant Cell. August 1, 2012; 24 (8): 3463-81.


Structure and permeation mechanism of a mammalian urea transporter., Levin EJ, Cao Y, Enkavi G, Quick M, Pan Y, Tajkhorshid E, Zhou M., Proc Natl Acad Sci U S A. July 10, 2012; 109 (28): 11194-9.


Structural basis of Wnt recognition by Frizzled., Janda CY, Waghray D, Levin AM, Thomas C, Garcia KC., Science. July 6, 2012; 337 (6090): 59-64.


Spatial regulation of BMP activity., Ramel MC, Hill CS., FEBS Lett. July 4, 2012; 586 (14): 1929-41.


Sequencing and characterizing odorant receptors of the cerambycid beetle Megacyllene caryae., Mitchell RF, Hughes DT, Luetje CW, Millar JG, Soriano-Agatón F, Hanks LM, Robertson HM., Insect Biochem Mol Biol. July 1, 2012; 42 (7): 499-505.


Structural organization of the nuclear pore permeability barrier., Liashkovich I, Meyring A, Oberleithner H, Shahin V., J Control Release. June 28, 2012; 160 (3): 601-8.


Sim2 prevents entry into the myogenic program by repressing MyoD transcription during limb embryonic myogenesis., Havis E, Coumailleau P, Bonnet A, Bismuth K, Bonnin MA, Johnson R, Fan CM, Relaix F, Shi DL, Duprez D., Development. June 1, 2012; 139 (11): 1910-20.                    


Single-molecule analysis of DNA replication in Xenopus egg extracts., Yardimci H, Loveland AB, van Oijen AM, Walter JC., Methods. June 1, 2012; 57 (2): 179-86.


Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors., Charvet CL, Robertson AP, Cabaret J, Martin RJ, Neveu C., Invert Neurosci. June 1, 2012; 12 (1): 43-51.


Specification of neural crest into sensory neuron and melanocyte lineages., Pavan WJ, Raible DW., Dev Biol. June 1, 2012; 366 (1): 55-63.


Synthesis and nicotinic receptor activity of chemical space analogues of N-(3R)-1-azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide (PNU-282,987) and 1,4-diazabicyclo[3.2.2]nonane-4-carboxylic acid 4-bromophenyl ester (SSR180711)., Bréthous L, Garcia-Delgado N, Schwartz J, Bertrand S, Bertrand D, Reymond JL., J Med Chem. May 24, 2012; 55 (10): 4605-18.


Suppression of intestinal calcium entry channel TRPV6 by OCRL, a lipid phosphatase associated with Lowe syndrome and Dent disease., Wu G, Zhang W, Na T, Jing H, Wu H, Peng JB., Am J Physiol Cell Physiol. May 15, 2012; 302 (10): C1479-91.


Specific domains of FoxD4/5 activate and repress neural transcription factor genes to control the progression of immature neural ectoderm to differentiating neural plate., Neilson KM, Klein SL, Mhaske P, Mood K, Daar IO, Moody SA., Dev Biol. May 15, 2012; 365 (2): 363-75.                        


Structure and stoichiometry of an accessory subunit TRIP8b interaction with hyperpolarization-activated cyclic nucleotide-gated channels., Bankston JR, Camp SS, DiMaio F, Lewis AS, Chetkovich DM, Zagotta WN., Proc Natl Acad Sci U S A. May 15, 2012; 109 (20): 7899-904.


Sigma-1 receptor alters the kinetics of Kv1.3 voltage gated potassium channels but not the sensitivity to receptor ligands., Kinoshita M, Matsuoka Y, Suzuki T, Mirrielees J, Yang J., Brain Res. May 3, 2012; 1452 1-9.


Stereospecific binding of a disordered peptide segment mediates BK channel inactivation., Gonzalez-Perez V, Zeng XH, Henzler-Wildman K, Lingle CJ., Nature. May 3, 2012; 485 (7396): 133-6.      


Saquinavir inhibits the malaria parasite's chloroquine resistance transporter., Martin RE, Butterworth AS, Gardiner DL, Kirk K, McCarthy JS, Skinner-Adams TS., Antimicrob Agents Chemother. May 1, 2012; 56 (5): 2283-9.

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